METHYL 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE-2-CARBOXYLATE synthesis

6synthesis methods

Product Name:METHYL 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE-2-CARBOXYLATE
CAS Number:111836-35-2
Molecular formula:C12H13NO2
Molecular Weight:203.24

81167-39-7 Synthesis

N-(DIPHENYLMETHYLENE)GLYCINE METHYL ESTER

81167-39-7
149 suppliers
$9.00/5g

768-03-6
102 suppliers
$62.00/250mg

METHYL 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE-2-CARBOXYLATE

111836-35-2
16 suppliers
$45.00/10mg

Yield:111836-35-2 78%

Reaction Conditions:

Stage #1: methyl N-(diphenylmethylene)glycinate;Phenyl vinyl ketonewith 1,8-diazabicyclo[5.4.0]undec-7-ene in dichloromethane at 5 - 20;Inert atmosphere;
Stage #2: with hydrogenchloride in dichloromethane;water at 20;Inert atmosphere;

References:

Liu, Penglin;Huo, Xiaohong;Li, Bowen;He, Rui;Zhang, Jiacheng;Wang, Tianhong;Xie, Fang;Zhang, Wanbin [Organic Letters,2018,vol. 20,# 20,p. 6564 - 6568] Location in patent:supporting information

1501-04-8
85 suppliers
$14.00/250mg

111836-35-2
16 suppliers
$45.00/10mg

References

METHYL ((PHENYLMETHYLIDENE)AMINO ACETAT&

66646-88-6
19 suppliers
inquiry

111836-35-2
16 suppliers
$45.00/10mg

References

4-Pentynoic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-5-phenyl-, methyl ester

291534-50-4
0 suppliers
inquiry

111836-35-2
16 suppliers
$45.00/10mg

References

71460-02-1 Synthesis

(2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-4-pentynoic acid methyl ester

71460-02-1
34 suppliers
inquiry

111836-35-2
16 suppliers
$45.00/10mg

References