ChemicalBook CAS DataBase List R-[1,1'-Binaphthalene]-2,2'-dicarboxylic acid 2,2'-dimethyl ester

R-[1,1'-Binaphthalene]-2,2'-dicarboxylic acid 2,2'-dimethyl ester synthesis

10synthesis methods

Product Name:R-[1,1'-Binaphthalene]-2,2'-dicarboxylic acid 2,2'-dimethyl ester
CAS Number:113567-21-8
Molecular formula:C24H18O4
Molecular Weight:370.4

2-Naphthalenecarboxylic acid, 1-broMo-, Methyl ester

89555-39-5
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R-[1,1'-Binaphthalene]-2,2'-dicarboxylic acid 2,2'-dimethyl ester

113567-21-8
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Yield:113567-21-8 90.2%

Reaction Conditions:

with copper at 190; for 8 h;Ullmann Condensation;

Steps:

8.6

6) in a dry 50 ml round-bottom flask by adding 0.3688g1-bromo-2-naphthalene carboxylic acid methyl ester and 1.34g copper powder, then heating to 190 °C, stirring 8h stop heating after, for three times 30 ml hot toluene extraction, extraction of the organic substances, combined with the organic layer, filtered, filtrate for rotary evaporimeter removing the solvent toluene, is separated through the chromatographic column white solid (2,2 the [...] -dicarboxylic acid methyl ester -1,1 the-binaphthyl [...] ) 0.14g, yield 90.2%.

References:

CN105541605,2016,A Location in patent:Paragraph 0082

20717-79-7 Synthesis