Sulfonium, (4-methylphenyl)diphenyl-, salt with 2-[(2,2-difluoro-2-sulfoacetyl)oxy]ethyl tricyclo[3.3.1.13,7]decane-1-carboxylate synthesis

Yield:1135815-31-4 81.5%

Reaction Conditions:

in dichloromethane;water; for 1 h;

Steps:

4.iii

(iii) 0.384 g of the compound (V) shown below was dissolved in 3.84 g of dichloromethane and 3.84 g of water, and then 0.40 g of the aforementioned compound (IV) was added thereto. The resultant was stirred for 1 hour, and then the organic layer was collected by fractionation. The organic layer was washed three times with 3.84 g of water. The organic layer thus obtained was concentrated and dried, thereby obtaining 0.44 g of the compound (VI) shown below (yield: 81.5%).

References:

EP2093213,2009,A1 Location in patent:Page/Page column 61