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2-BENZOYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 48 percent / conc. hydrochloric acid / 4 h / 100 °C
2: 71 percent / aq. NaOH / acetone

References:

Shinkai, Hisashi;Toi, Koji;Kumashiro, Izumi;Seto, Yoshiko;Fukuma, Mariko;et al. [Journal of Medicinal Chemistry,1988,vol. 31,# 11,p. 2092 - 2097]

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