2-chloro-N-((3S,4S)-4-hydroxy-1-tosylpyrrolidin-3-yl)-N-((R)-1-phenylethyl)acetaMide synthesis

1synthesis methods

Product Name:2-chloro-N-((3S,4S)-4-hydroxy-1-tosylpyrrolidin-3-yl)-N-((R)-1-phenylethyl)acetaMide
CAS Number:1159908-19-6
Molecular formula:C21H25ClN2O4S
Molecular Weight:436.95

(3S,4S)-4-((R)-1-phenylethylaMino)-1-tosylpyrrolidin-3-ol

1159908-18-5
8 suppliers
$712.00/50mg

79-04-9 Synthesis

79-04-9
354 suppliers
$12.00/5g

2-chloro-N-((3S,4S)-4-hydroxy-1-tosylpyrrolidin-3-yl)-N-((R)-1-phenylethyl)acetaMide

1159908-19-6
8 suppliers
$892.00/50mg

Yield:1159908-19-6 80%

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine in tetrahydrofuran;

References:

Hong, Jian;Zhang, Zonghua;Lei, Huoxing;Cheng, Haiying;Hu, Yufang;Yang, Wanliang;Liang, Yinglin;Das, Debasis;Chen, Shu-Hui;Li, Ge [Tetrahedron Letters,2009,vol. 50,# 21,p. 2525 - 2528] Location in patent:body text