Benzo[b]thiophene-2-carbonitrile, 6-bromo-3-chloro- synthesis

2synthesis methods

Product Name:Benzo[b]thiophene-2-carbonitrile, 6-bromo-3-chloro-
CAS Number:1172746-65-4
Molecular formula:C9H3BrClNS
Molecular Weight:272.55

1200-07-3
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$17.00/25g

Benzo[b]thiophene-2-carbonitrile, 6-bromo-3-chloro-

1172746-65-4
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: pyridine; thionyl chloride / chlorobenzene / 50 - 115 °C
2: ammonia / methanol
3: triethylamine; trifluoroacetic anhydride / dichloromethane

References:

Kuduk, Scott D.;Chang, Ronald K.;Di Marco, Christina N.;Dipardo, Robert M.;Cook, Sean P.;Cato, Matthew J.;Jovanovska, Aneta;Urban, Mark O.;Leitl, Michael;Spencer, Robert H.;Kane, Stefanie A.;Hartman, George D.;Bilodeau, Mark T. [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 14,p. 4255 - 4258]

75212-27-0 Synthesis

6-BROMO-3-CHLORO-BENZO[B]THIOPHENE-2-CARBONYL CHLORIDE

75212-27-0
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$58.00/100mg

1172746-65-4
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References