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methyl(R)-3-cyclopentyl-2-(((trifluoromethyl)sulfonyl)oxy)propanoate synthesis

3synthesis methods
(R)-Methyl 3-cyclopentyl-2-hydroxypropanoate

1174013-24-1
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methyl(R)-3-cyclopentyl-2-(((trifluoromethyl)sulfonyl)oxy)propanoate

1174013-25-2
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Yield:1174013-25-2 96%

Reaction Conditions:

with 2,6-dimethylpyridine in dichloromethane at 0; for 0.5 h;

References:

Pfefferkorn, Jeffrey A.;Lou, Jihong;Minich, Martha L.;Filipski, Kevin J.;He, Mingying;Zhou, Ru;Ahmed, Syed;Benbow, John;Perez, Angel-Guzman;Tu, Meihua;Litchfield, John;Sharma, Raman;Metzler, Karen;Bourbonais, Francis;Huang, Cong;Beebe, David A.;Oates, Peter J. [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 12,p. 3247 - 3252] Location in patent:scheme or table