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ChemicalBook CAS DataBase List 1-Benzenesulfonyl-3-broMo-1H-pyrrolo[2,3-c]pyridine
1174038-64-2

1-Benzenesulfonyl-3-broMo-1H-pyrrolo[2,3-c]pyridine synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: bromine; sodium hydrogencarbonate / methanol / 3 h / 0 - 20 °C / Inert atmosphere
2: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 1 h / 0 °C / Inert atmosphere

References:

Kettle, Jason G.;Ballard, Peter;Bardelle, Catherine;Cockerill, Mark;Colclough, Nicola;Critchlow, Susan E.;Debreczeni, Judit;Fairley, Gary;Fillery, Shaun;Graham, Mark A.;Goodwin, Louise;Guichard, Sylvie;Hudson, Kevin;Ward, Richard A.;Whittaker, David [Journal of Medicinal Chemistry,2015,vol. 58,# 6,p. 2834 - 2844]