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ChemicalBook CAS DataBase List 3-bromo-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one

3-bromo-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one synthesis

3synthesis methods
1-(4-bromo-3-hydroxythiophen-2-yl)-3-morpholinopropane-1,3-dione

1174429-38-9
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3-bromo-5-(morpholin-4-yl)-7H-thieno[3,2-b]pyran-7-one

1174429-23-2
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Yield:1174429-23-2 82%

Reaction Conditions:

with trifluoromethylsulfonic anhydride in dichloromethane at 20;

References:

Morales, Guillermo A.;Garlich, Joseph R.;Su, Jingdong;Peng, Xiaodong;Newblom, Jessica;Weber, Kevin;Durden, Donald L. [Journal of Medicinal Chemistry,2013,vol. 56,# 5,p. 1922 - 1939]