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ChemicalBook CAS DataBase List 1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER

1-METHYL-1H-PYRAZOLE-3,5-DICARBOXYLIC ACID 3-METHYL ESTER synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 47 percent / KMnO4 / H2O / Heating
2: thionyl chloride / methanol / 24 h / Heating
3: K2CO3 / acetone / 1 h / Heating
4: 89 percent / KOH / methanol / 24 h / 20 °C

References:

Lee, Ho H.;Cain, Bruce F.;Denny, William A.;Buckleton, John S.;Clark, George R. [Journal of Organic Chemistry,1989,vol. 54,# 2,p. 428 - 431]