5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methyl-Benzoic acid methyl ester synthesis

4synthesis methods

Product Name:5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methyl-Benzoic acid methyl ester
CAS Number:1184301-84-5
Molecular formula:C15H21NO4
Molecular Weight:279.33

24424-99-5 Synthesis

24424-99-5
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5-Cyano-2-methyl-benzoic acid methyl ester

103261-68-3
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5-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]-2-methyl-Benzoic acid methyl ester

1184301-84-5
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Yield:1184301-84-5 85%

Reaction Conditions:

with sodium tetrahydroborate;nickel(II) chloride hexahydrate in methanol at 0 - 23; for 2.25 h;

References:

Ghosh, Arun K.;Takayama, Jun;Aubin, Yoann;Ratia, Kiira;Chaudhuri, Rima;Baez, Yahira;Sleeman, Katrina;Coughlin, Melissa;Nichols, Daniel B.;Mulhearn, Debbie C.;Prabhakar, Bellur S.;Baker, Susan C.;Johnson, Michael E.;Mesecar, Andrew D. [Journal of Medicinal Chemistry,2009,vol. 52,# 16,p. 5228 - 5240] Location in patent:experimental part

1975-52-6
280 suppliers
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1184301-84-5
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References

77324-87-9 Synthesis

77324-87-9
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1184301-84-5
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References

5-AMINO-2-METHYL-BENZOIC ACID METHYL ESTER

18595-12-5
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1184301-84-5
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References