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3(2H)-Isoquinolinone, 7-fluoro-1,4-dihydro-2-methyl- synthesis

1synthesis methods
-

Yield:1199813-81-4 89%

Reaction Conditions:

with phosphorus pentoxide in methanesulfonic acid at 80; for 1 h;

References:

Ulysse, Luckner G.;Yang, Qiang;McLaws, Mark D.;Keefe, Daniel K.;Guzzo, Peter R.;Haney, Brian P. [Organic Process Research and Development,2010,vol. 14,# 1,p. 225 - 228] Location in patent:experimental part