ChemicalBook CAS DataBase List 12-methyl-1-tridecanol

12-methyl-1-tridecanol synthesis

12synthesis methods

Product Name:12-methyl-1-tridecanol
CAS Number:21987-21-3
Molecular formula:C14H30O
Molecular Weight:214.39

53463-68-6 Synthesis

53463-68-6
203 suppliers
$6.00/1g

926-62-5 Synthesis

926-62-5
169 suppliers
$75.20/100ml

21987-21-3
28 suppliers
$165.00/250mg

Yield: 100%

Reaction Conditions:

with copper(l) chloride in tetrahydrofuran at 0 - 20; for 2 h;Inert atmosphere;

Steps:

Synthesis of Compound 18
0 ° C, nitrogen protection, will10-bromofurfuryl alcohol(1 eqv) and a catalytic amount of cuprous chloride dissolved in dry tetrahydrofuran,Add isobutylmagnesium bromide (2.5 eqv),React at room temperature for 2 hours,Quenching the reaction with saturated ammonium chloride,Extracted with ethyl acetate,Saturated brine,The organic phase is dry,Steamed,Column chromatography gave Intermediate 18,The yield was 100%.

References:

Chinese Academy Of Sciences Ecological Environment Research Center;Du Yuguo;Geng Jialin;Liu Sijin CN109908115, 2019, A Location in patent:Paragraph 0027-0028