SODIUM 5-(PYRIDIN-3-YL)-1,3,4-THIADIAZOLE-2-CARBOXYLATE synthesis

2synthesis methods

Product Name:SODIUM 5-(PYRIDIN-3-YL)-1,3,4-THIADIAZOLE-2-CARBOXYLATE
CAS Number:1201199-06-5
Molecular formula:C8H6N3NaO2S
Molecular Weight:231.2

1,3,4-Thiadiazole-2-carboxylic acid, 5-(3-pyridinyl)-, ethyl ester

1201199-05-4
1 suppliers
inquiry

SODIUM 5-(PYRIDIN-3-YL)-1,3,4-THIADIAZOLE-2-CARBOXYLATE

1201199-06-5
4 suppliers
inquiry

Yield:1201199-06-5 92%

Reaction Conditions:

with sodium ethanolate in ethanol;water at 20; for 0.666667 h;Cooling with ice bath;

Steps:

7.3 sodium 5-pyridin-3-yl[1,3,4]thiadiazole-2-carboxylate

1.5 g (6.37 mmol) of the thiadiazolecarboxylic ester and 2.3 ml (6.3 mmol) of a 21% solution of sodium ethoxide in ethanol were stirred in a mixture of 23 ml of ethanol and 7.5 ml of water at room temperature for 30 minutes, and stirred for another 10 min with ice bath cooling. The precipitated product was filtered off with suction, washed twice with ether and dried on a rotary evaporator. Yield: 1.35 g (92% of theory)

References:

US2011/98287,2011,A1 Location in patent:Page/Page column 25

553-53-7 Synthesis

553-53-7
210 suppliers
$5.00/5g

1201199-06-5
4 suppliers
inquiry

References