ChemicalBook CAS DataBase List 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro-

1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro- synthesis

1synthesis methods

Product Name:1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro-
CAS Number:1204475-64-8
Molecular formula:C8H5ClN2O2
Molecular Weight:196.59

1H-PYRROLO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID

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1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-chloro-

1204475-64-8
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Yield:-

Reaction Conditions:

with N-chloro-succinimide in chloroform

Steps:

2
Example 2Synthesis of 3-chloro-lH-pyrrolo [2 , 3-jb]pyridine-2-carboxylic acid2 3Treatment of 2 with JV-chlorosuccinimide in chloroform gives 3-chloro-lH-pyrrolo[2, 3-jb]pyridine-2-carboxylic acid (3) .

References:

IRONWOOD PHARMACEUTICALS INCORPORATED;LUDRIGAN, Regina;JEFFREY, John;MERMERIAN, Ara WO2010/5528, 2010, A2 Location in patent:Page/Page column 87