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Propanoic acid, 3,3,3-trifluoro-2-methyl-, ethyl ester, (+)- synthesis

5synthesis methods
Propanedioic acid, (bromodifluoromethyl)methyl-, diethyl ester

82477-46-1
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Propanoic acid, 3,3,3-trifluoro-2-methyl-, ethyl ester, (+)-

121773-36-2
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Yield:121773-36-2 44%

Reaction Conditions:

with potassium fluoride in dimethyl sulfoxide at 170; for 2 h;

References:

Purrington, Suzanne, T.;Everett, T. Stephen;Bumgardner, Carl L. [Tetrahedron Letters,1984,vol. 25,# 13,p. 1329 - 1332] Everett, Stephen T.;Purrington, Suzanne T.;Bumgardner, Carl L. [Journal of Organic Chemistry,1984,vol. 49,# 20,p. 3702 - 3706]