2-phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-Thiazole synthesis

2synthesis methods

Product Name:2-phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-Thiazole
CAS Number:1225053-32-6
Molecular formula:C15H18BNO2S
Molecular Weight:287.18

1826-11-5
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76-09-5 Synthesis

76-09-5
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$10.00/1g

2-phenyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-Thiazole

1225053-32-6
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Yield:1225053-32-6 86%

Reaction Conditions:

Stage #1: 2-phenylthiazolewith n-butyllithium in tetrahydrofuran;hexane at -80 - -50;Inert atmosphere;
Stage #2: with Triisopropyl borate in tetrahydrofuran;hexane at -90 - 20;
Stage #3: 2,3-dimethyl-2,3-butane diolwith acetic acid in tetrahydrofuran;hexane;

References:

Schnuerch, Michael;Haemmerle, Johanna;Mihovilovic, Marko D.;Stanetty, Peter [Synthesis,2010,# 5,art. no. T19509SS,p. 837 - 843] Location in patent:experimental part

1826-11-5
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$33.00/1g

61676-62-8 Synthesis

2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

61676-62-8
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$11.19/5G

1225053-32-6
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References