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ChemicalBook CAS DataBase List 2,3-DIHYDRO-PYRAZINE-1,4-DICARBOXYLIC ACID 1-BENZYL ESTER 4-TERT-BUTYL ESTER

2,3-DIHYDRO-PYRAZINE-1,4-DICARBOXYLIC ACID 1-BENZYL ESTER 4-TERT-BUTYL ESTER synthesis

1synthesis methods
1,4-Piperazinedicarboxylic acid, 2-hydroxy-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester

1228675-26-0
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Yield:1228675-27-1 5.41 g

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine;acetyl chloride in benzene; for 1.5 h;Reflux;

References:

Taylor, Rivka R.R.;Twin, Heather C.;Wen, Wendy W.;Mallot, Rebecca J.;Lough, Alan J.;Gray-Owen, Scott D.;Batey, Robert A. [Tetrahedron,2010,vol. 66,# 18,p. 3370 - 3377] Location in patent:experimental part