(R)-Ethyl 2-(piperidin-3-yl)acetic acid hydrochloride synthesis
- Product Name:(R)-Ethyl 2-(piperidin-3-yl)acetic acid hydrochloride
- CAS Number:1233200-48-0
- Molecular formula:C9H17NO2HCl
- Molecular Weight:207.6977
6419-36-9
392 suppliers
$10.00/5g
1233200-48-0
33 suppliers
$163.00/250mg
Yield:-
Steps:
Multi-step reaction with 5 steps
1: thionyl chloride / 16.25 h / 0 °C / Reflux
2: acetonitrile / 12 h / Reflux
3: 5%-palladium/activated carbon; hydrogen / ethanol / 8 h / 20 °C / 7500.75 Torr
4: (S)-Mandelic acid / ethyl acetate / 4 h / Reflux; Resolution of racemate
5: hydrogenchloride / diethyl ether / 2 h / 0 °C
References:
Zhu, Ying-Guang;Kan, Hong-Zhu;Jiang, Li-Qin;Hu, Wen-Hao [Synthetic Communications,2012,vol. 42,# 8,p. 1137 - 1145]
188883-57-0
8 suppliers
inquiry
1233200-48-0
33 suppliers
$163.00/250mg
39931-77-6
184 suppliers
$10.00/1g
1233200-48-0
33 suppliers
$163.00/250mg
1232140-16-7
1 suppliers
inquiry
1233200-48-0
33 suppliers
$163.00/250mg
3423-47-0
3 suppliers
inquiry
1233200-48-0
33 suppliers
$163.00/250mg