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ChemicalBook CAS DataBase List 3-(tert-butoxycarbonyl)-3-azabicyclo[4.1.0]heptane-1-carboxylic acid
1239421-67-0

3-(tert-butoxycarbonyl)-3-azabicyclo[4.1.0]heptane-1-carboxylic acid synthesis

5synthesis methods
3-(tert-butyl) 1-methyl 3-azabicyclo[4.1.0]heptane-1,3-dicarboxylate

1192688-49-5
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3-(tert-butoxycarbonyl)-3-azabicyclo[4.1.0]heptane-1-carboxylic acid

1239421-67-0
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Yield:1239421-67-0 86%

Reaction Conditions:

with water;lithium hydroxide in tetrahydrofuran;methanol at 20; for 3 h;chemoselective reaction;

References:

Napolitano, Carmela;Borriello, Manuela;Cardullo, Francesca;Donati, Daniele;Paio, Alfredo;Manfredini, Stefano [Tetrahedron,2010,vol. 66,# 29,p. 5492 - 5497] Location in patent:experimental part