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1239766-69-8

N'-{(E)-[4-(propan-2-yl)phenyl]methylidene}pyrazine-2-carbohydrazide synthesis

1synthesis methods
768-05-8 Synthesis
Pyrazinoic acid hydrazide

768-05-8
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N'-{(E)-[4-(propan-2-yl)phenyl]methylidene}pyrazine-2-carbohydrazide

1239766-69-8
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Yield:1239766-69-8 77%

Reaction Conditions:

with hydrogenchloride in ethanol;water at 20; for 2 h;diastereoselective reaction;

References:

Silva, Yolanda Karla Cupertino Da;Augusto, Cristina Villarinho;Barbosa, Maria Leticia De Castro;Melo, Gabriela Muniz De Albuquerque;Queiroz, Aline Cavalcanti De;Dias, Thays De Lima Matos Freire;Junior, Walfrido Bispo;Barreiro, Eliezer J.;Lima, Lidia Moreira;Alexandre-Moreira, Magna Suzana [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 14,p. 5007 - 5015] Location in patent:experimental part