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1-methyl-4-((6-methylpyridin-3-yl)methyl)piperazine synthesis

1synthesis methods
3430-13-5 Synthesis
5-Bromo-2-methylpyridine

3430-13-5
421 suppliers
$5.00/5g

Potassium 1-methyl-4-trifluoroboratomethylpiperazine

1015484-22-6
50 suppliers
$33.00/1g

1-methyl-4-((6-methylpyridin-3-yl)methyl)piperazine

1245646-56-3
6 suppliers
inquiry

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Yield:1245646-56-3 57%

Reaction Conditions:

with C52H67ClFeNPPd;caesium carbonate in tetrahydrofuran;water at 80; for 12 h;Suzuki-Miyaura cross-coupling;

References:

Zou, Dapeng;Cui, Hongmeng;Qin, Lijin;Li, Jingya;Wu, Yangjie;Wu, Yusheng [Synlett,2011,# 3,art. no. S05710ST,p. 349 - 356] Location in patent:scheme or table