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ChemicalBook CAS DataBase List 2-(5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propan-2-ol

2-(5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propan-2-ol synthesis

6synthesis methods
29681-44-5 Synthesis
Methyl 5-bromonicotinate

29681-44-5
302 suppliers
$6.00/5g

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Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: diethyl ether; tetrahydrofuran / 1.5 h / 18 - 20 °C
1.2: 0 °C
2.1: potassium acetate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 90 °C / Inert atmosphere

References:

ELI LILLY AND COMPANY US2012/184577, 2012, A1

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