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1261296-29-0

(1S,2R,3R,8S)-4-(Hydroxymethyl)cubane-1-carboxylic acid synthesis

3synthesis methods
-

Yield:1261296-29-0 89%

Reaction Conditions:

Stage #1: 4-(methoxycarbonyl)-1-cubanecarboxylic acidwith sodium tetrahydroborate in water at 20; for 3 h;
Stage #2: with hydrogenchloride in water at 0;

References:

Romanova;Barinova;Zakharov;Eremenko;Aleksandrov;Eremenko [Russian Chemical Bulletin,2010,vol. 59,# 5,p. 1051 - 1055] Location in patent:experimental part