ChemicalBook CAS DataBase List 4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide

4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide synthesis

4synthesis methods

Product Name:4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide
CAS Number:1261576-81-1
Molecular formula:C25H24ClN3O3S2
Molecular Weight:514.06

118-31-0
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4-Chloro-N-(naphthalen-1-ylmethyl)-5-(3-(piperazin-1-yl)phenoxy)thiophene-2-sulfonamide

1261576-81-1
29 suppliers
$30.00/5mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: triethylamine / dichloromethane / 2 h / 20 °C / Inert atmosphere
2.1: sodium hydride / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere
2.2: 2 h / 0 - 20 °C / Inert atmosphere
3.1: caesium carbonate / N,N-dimethyl-formamide / 2.5 h / 80 °C / Inert atmosphere
4.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C / Inert atmosphere

References:

NORTH CAROLINA CENTRAL UNIVERSITY;WILLIAMS, Alfred L.;IBEANU, Gordon;DANDEPALLY, Srinivasa WO2011/84503, 2011, A1

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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1261576-81-1
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References

1000210-73-0
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1261576-81-1
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References

1-(3-HYDROXY-PHENYL)-PIPERAZINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER

198627-86-0
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$55.00/100mg

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1261576-81-1
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References