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ChemicalBook CAS DataBase List 1H-Indole-2-carboxylicacid,5,6-dihydroxy-1-methyl-(9CI)

1H-Indole-2-carboxylicacid,5,6-dihydroxy-1-methyl-(9CI) synthesis

4synthesis methods
5,6-dimethoxy-1-methyl-1H-indole-2-carboxylic ethyl ester

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1H-Indole-2-carboxylicacid,5,6-dihydroxy-1-methyl-(9CI)

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: lithium hydroxide / ethanol / 50 °C
2: boron tribromide / dichloromethane / -15 - 20 °C

References:

Deng, Huayun;Fang, Ye [ACS Medicinal Chemistry Letters,2012,vol. 3,# 7,p. 550 - 554]