ChemicalBook CAS DataBase List Cyclohexaneacetic acid, 4,4-difluoro-α-[[(phenylmethoxy)carbonyl]amino]-, (αS)-

Cyclohexaneacetic acid, 4,4-difluoro-α-[[(phenylmethoxy)carbonyl]amino]-, (αS)- synthesis

5synthesis methods

Product Name:Cyclohexaneacetic acid, 4,4-difluoro-α-[[(phenylmethoxy)carbonyl]amino]-, (αS)-
CAS Number:1266228-88-9
Molecular formula:C16H19F2NO4
Molecular Weight:327.33

Cyclohexaneacetic acid, 4,4-difluoro-α-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (αS)-

1241377-40-1
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Cyclohexaneacetic acid, 4,4-difluoro-α-[[(phenylmethoxy)carbonyl]amino]-, (αS)-

1266228-88-9
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Yield:1266228-88-9 95%

Reaction Conditions:

with lithium hydroxide monohydrate in tetrahydrofuran;water at 0 - 20; for 2 h;

References:

Hashimoto, Kentaro;Saito, Bunnai;Miyamoto, Naoki;Oguro, Yuya;Tomita, Daisuke;Shiokawa, Zenyu;Asano, Moriteru;Kakei, Hiroyuki;Taya, Naohiro;Kawasaki, Masanori;Sumi, Hiroyuki;Yabuki, Masato;Iwai, Kenichi;Yoshida, Sei;Yoshimatsu, Mie;Aoyama, Kazunobu;Kosugi, Yohei;Kojima, Takashi;Morishita, Nao;Dougan, Douglas R.;Snell, Gyorgy P.;Imamura, Shinichi;Ishikawa, Tomoyasu [Journal of Medicinal Chemistry,2013,vol. 56,# 3,p. 1228 - 1246] Location in patent:supporting information

1,4-Dioxaspiro[4.5]decane-8-acetic acid, α-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (αS)-

873581-24-9
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1266228-88-9
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Cyclohexaneacetic acid, 4-oxo-α-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (αS)-

1241377-38-7
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1266228-88-9
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References

22515-18-0 Synthesis

22515-18-0
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$5.00/100mg

1266228-88-9
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References

100945-15-1 Synthesis

methyl ([(benzyloxy)carbonyl]amino)-(dimethoxyphosphoryl)acetate

100945-15-1
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1266228-88-9
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References