ChemicalBook CAS DataBase List 6-TERT-BUTYL 4-ETHYL 2-(METHYLTHIO)-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDINE-4,6(5H)-DICARBOXYLATE

6-TERT-BUTYL 4-ETHYL 2-(METHYLTHIO)-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDINE-4,6(5H)-DICARBOXYLATE synthesis

2synthesis methods

Product Name:6-TERT-BUTYL 4-ETHYL 2-(METHYLTHIO)-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDINE-4,6(5H)-DICARBOXYLATE
CAS Number:1279816-50-0
Molecular formula:C16H23N3O4S
Molecular Weight:353.44

79099-07-3 Synthesis

79099-07-3
543 suppliers
$5.00/5g

6-TERT-BUTYL 4-ETHYL 2-(METHYLTHIO)-7,8-DIHYDROPYRIDO[4,3-D]PYRIMIDINE-4,6(5H)-DICARBOXYLATE

1279816-50-0
13 suppliers
inquiry

Yield:-

Steps:

Multi-step reaction with 3 steps
1: toluene / 18 h / Reflux; Dean-Stark; Inert atmosphere
2: triethylamine / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere
3: triethylamine / ethanol / 18 h / Inert atmosphere; Reflux

References:

Piotrowski, David W.;Futatsugi, Kentaro;Warmus, Joseph S.;Orr, Suvi T. M.;Freeman-Cook, Kevin D.;Londregan, Allyn T.;Wei, Liuqing;Jennings, Sandra M.;Herr, Michael;Coffey, Steven B.;Jiao, Wenhua;Storer, Gregory;Hepworth, David;Wang, Jian;Lavergne, Sophie Y.;Chin, Janice E.;Hadcock, John R.;Brenner, Martin B.;Wolford, Angela C.;Janssen, Ann M.;Roush, Nicole S.;Buxton, Joanne;Hinchey, Terri;Kalgutkar, Amit S.;Sharma, Raman;Flynn, Declan A. [ACS Medicinal Chemistry Letters,2013,vol. 4,# 1,p. 63 - 68]

1(2H)-Pyridinecarboxylic acid, 3,6-dihydro-4-(4-morpholinyl)-, 1,1-dimethylethyl ester

217807-98-2
2 suppliers
inquiry

1279816-50-0
13 suppliers
inquiry

References