![](/CAS/20200611/GIF/1286711-20-3.gif)
2-({[(9H-fluoren-9-yl)methoxy]carbonyl}[2-(4-methoxyphenyl)ethyl]amino)acetic acid synthesis
- Product Name:2-({[(9H-fluoren-9-yl)methoxy]carbonyl}[2-(4-methoxyphenyl)ethyl]amino)acetic acid
- CAS Number:1286711-20-3
- Molecular formula:C26H25NO5
- Molecular Weight:431.48
![Glycine, N-[2-(4-methoxyphenyl)ethyl]-, ethyl ester](/CAS/20210305/GIF/1021046-51-4.gif)
1021046-51-4
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![N-(9-Fluorenylmethoxycarbonyloxy)succinimide](/CAS/GIF/82911-69-1.gif)
82911-69-1
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$7.00/25g
![2-({[(9H-fluoren-9-yl)methoxy]carbonyl}[2-(4-methoxyphenyl)ethyl]amino)acetic acid](/CAS/20200611/GIF/1286711-20-3.gif)
1286711-20-3
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Yield:1286711-20-3 79%
Reaction Conditions:
Stage #1: N-[2-(4-methoxyphenyl)ethyl]glycine ethyl esterwith sodium hydroxide in methanol; for 0.5 h;Inert atmosphere;
Stage #2: N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimidewith hydrogenchloride in 1,4-dioxane;water at 0 - 20;Inert atmosphere;
References:
Einsiedel, Jürgen;Held, Cornelia;Hervet, Maud;Plomer, Manuel;Tschammer, Nuska;Hübner, Harald;Gmeiner, Peter [Journal of Medicinal Chemistry,2011,vol. 54,# 8,p. 2915 - 2923] Location in patent:supporting information; experimental part
![4-Methoxyphenethylamine](/CAS/GIF/55-81-2.gif)
55-81-2
248 suppliers
$39.96/5g
![2-({[(9H-fluoren-9-yl)methoxy]carbonyl}[2-(4-methoxyphenyl)ethyl]amino)acetic acid](/CAS/20200611/GIF/1286711-20-3.gif)
1286711-20-3
12 suppliers
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