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ChemicalBook CAS DataBase List 2-chloro-5-ethyl-3H-pyrrolo[3,2- d]pyrimidin-4(5H)-one

2-chloro-5-ethyl-3H-pyrrolo[3,2- d]pyrimidin-4(5H)-one synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) NaH / 1.) MeCN, RT, 30 min, 2.) a) 0-5 deg C, 15 min, b) RT, overnight
2: 88 percent / NaOH / dioxane / 1 h / Heating

References:

Girgis, Nabih S.;Michael, Maged A.;Smee, Donald F.;Alaghamandan, Hassan A.;Robins, Roland K.;Cottam, Howard B. [Journal of Medicinal Chemistry,1990,vol. 33,# 10,p. 2750 - 2755]

129872-82-8 Synthesis
2,4-dichloro-5-ethyl-
5H-pyrrolo[3,2-d]pyrimidine

129872-82-8
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2-chloro-5-ethyl-3H-pyrrolo[3,2-
d]pyrimidin-4(5H)-one

129872-85-1
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