Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (S)- (9CI) synthesis
1synthesis methods
- Product Name:Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (S)- (9CI)
- CAS Number:131349-34-3
- Molecular formula:C45H61N4O9PSi
- Molecular Weight:861.05
Yield:131349-34-3 92%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in tetrahydrofuran at 0 - 20; for 5 h;
References:
Xu, Jianfeng;Duffy, Colm D.;Chan, Christopher K. W.;Sutherland, John D. [Journal of Organic Chemistry,2014,vol. 79,# 8,p. 3311 - 3326]