ChemicalBook CAS DataBase List 2,4-Dichloro-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline

2,4-Dichloro-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline synthesis

13synthesis methods

Product Name:2,4-Dichloro-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline
CAS Number:1320288-30-9
Molecular formula:C16H19Cl2N3O2
Molecular Weight:356.25

1320288-29-6 Synthesis

6-Methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline-2,4-diol

1320288-29-6
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2,4-Dichloro-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline

1320288-30-9
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Yield:1320288-30-9 69%

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine;trichlorophosphate at 100; for 2 h;Inert atmosphere;

References:

Rabal, Obdulia;José-Enériz, Edurne San;Agirre, Xabier;Sánchez-Arias, Juan Antonio;Vilas-Zornoza, Amaia;Ugarte, Ana;De Miguel, Irene;Miranda, Estíbaliz;Garate, Leire;Fraga, Mario;Santamarina, Pablo;Perez, Raul Fernandez;Ordo?ez, Raquel;Sáez, Elena;Roa, Sergio;García-Barchino, María José;Martínez-Climent, José Angel;Liu, Yingying;Wu, Wei;Xu, Musheng;Prosper, Felipe;Oyarzabal, Julen [Journal of Medicinal Chemistry,2018,vol. 61,# 15,p. 6518 - 6545]

Methyl 5-Methoxy-2-nitro-4-(3-(pyrrolidin-1-yl)propoxy)benzoate

1320288-23-0
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1320288-30-9
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Methyl 2-aMino-5-Methoxy-4-(3-(pyrrolidin-1-yl)propoxy)benzoate

1320288-24-1
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1320288-30-9
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3943-74-6 Synthesis

3943-74-6
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1320288-30-9
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References

111627-40-8 Synthesis

Methyl 4-(3-chloropropoxy)-3-Methoxybenzoate

111627-40-8
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1320288-30-9
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References