![](/CAS/20180702/GIF/1321518-03-9.gif)
2-(trifluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpyridine synthesis
- Product Name:2-(trifluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpyridine
- CAS Number:1321518-03-9
- Molecular formula:C13H17BF3NO2
- Molecular Weight:287.09
![CHEMPACIFIC 38183](/CAS/GIF/1620-72-0.gif)
1620-72-0
57 suppliers
$24.00/1g
![Bis(pinacolato)diboron](/CAS/20180808/GIF/73183-34-3.gif)
73183-34-3
567 suppliers
$6.00/5g
![2-(trifluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpyridine](/CAS/20180702/GIF/1321518-03-9.gif)
1321518-03-9
22 suppliers
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Yield:1321518-03-9 83%
Reaction Conditions:
Stage #1: bis(pinacol)diboranewith (1,5-cyclooctadiene)(methoxy)iridium(I) dimer;4,4'-di-tert-butyl-2,2'-bipyridine at 50; for 0.166667 h;Inert atmosphere;
Stage #2: 2-methyl-6-(trifluoromethyl)pyridine at 50; for 6 h;Inert atmosphere;
References:
Congreve, Miles;Andrews, Stephen P.;Doré, Andrew S.;Hollenstein, Kaspar;Hurrell, Edward;Langmead, Christopher J.;Mason, Jonathan S.;Ng, Irene W.;Tehan, Benjamin;Zhukov, Andrei;Weir, Malcolm;Marshall, Fiona H. [Journal of Medicinal Chemistry,2012,vol. 55,# 5,p. 1898 - 1903] Location in patent:experimental part
![2-Chloro-6-(trifluoromethyl)pyridine](/CAS/GIF/39890-95-4.gif)
39890-95-4
336 suppliers
$5.00/1g
![2-(trifluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-methylpyridine](/CAS/20180702/GIF/1321518-03-9.gif)
1321518-03-9
22 suppliers
inquiry