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N-Methyl-N-({6-[(methylamino)methyl]-pyridin-2-yl}methyl)amine synthesis

2synthesis methods
-

Yield:134956-67-5 90%

Reaction Conditions:

Stage #1: 2,6-bis(chloromethyl)pyridine;methylamine in water at 20;
Stage #2: with sodium hydroxide in water;

References:

Rovira, Mireia;Ja?íková, Lucie;Andris, Erik;Acu?a-Parés, Ferran;Soler, Marta;Güell, Imma;Wang, Ming-Zheng;Gómez, Laura;Luis, Josep M.;Roithová, Jana;Ribas, Xavi [Chemical Communications,2017,vol. 53,# 62,p. 8786 - 8789] Location in patent:supporting information