(E)-1-(4-CHLOROPHENYL)-3-(2-FLUOROPHENYL)-2-PROPEN-1-ONE synthesis
1synthesis methods
- Product Name:(E)-1-(4-CHLOROPHENYL)-3-(2-FLUOROPHENYL)-2-PROPEN-1-ONE
- CAS Number:1352574-46-9
- Molecular formula:C15H10ClFO
- Molecular Weight:260.69
Yield:-
Reaction Conditions:
Stage #1:para-chloroacetophenone with lithium hydroxide in ethanol at 25 - 30; for 0.583333 h;
Stage #2:2-Fluorobenzaldehyde in ethanolFurther stages.;Claisen-Schmidt condensation;
References:
Sharma, Gaurav;Kumar, Raj;Chakraborti, Asit K. [Tetrahedron Letters,2008,vol. 49,# 27,p. 4269 - 4271]