ChemicalBook CAS DataBase List (S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediaMine

(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediaMine synthesis

3synthesis methods

Product Name:(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediaMine
CAS Number:1373869-91-0
Molecular formula:C11H17N3O2
Molecular Weight:223.27

67-56-1 Synthesis

67-56-1
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104632-26-0
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(S)-4,5,6,7-Tetrahydro-N2,N6-propionyl-2,6-benzothiazolediaMine

1373869-91-0
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2-Pyrrolidineacetic acid, 5-[(aminocarbonyl)imino]-1-propyl-, methyl ester, (2S,5E)-

1373869-92-1
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Yield:1373869-91-0 455 mg ，1373869-92-1 129 mg

Reaction Conditions:

with oxygen;Rose Bengal lactone for 6 h;Irradiation;

Steps:

Photo-degradation in liquid state

Pramipexole free base (2.0 g) and rosebengal (0.1 g) were dissolved in MeOH (500 mL). The mixture was irradiated with bubbling oxygen under fluorescent lamp for 6 h. Then the reaction mixture was concentrated, and chromatographed over silica gel, using AcOEt-MeOH (9:1 to 8:2) as eluent to give 3 (455 mg) and 4 (129 mg).

References:

Nishimura, Eiji;Kugimiya, Aya;Naoki, Hideo;Hamanaka, Nobuyuki [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 8,p. 2951 - 2953] Location in patent:experimental part

2-Pyrrolidineacetic acid, 5-[(aminothioxomethyl)imino]-1-propyl-, methyl ester, (2S,5E)-

1373869-93-2
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1373869-91-0
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References

104632-26-0
309 suppliers
$8.00/50mg

1373869-91-0
11 suppliers
inquiry

References