2-Thiophenecarboxylic acid, 5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]- synthesis

4synthesis methods

Product Name:2-Thiophenecarboxylic acid, 5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-
CAS Number:138899-69-1
Molecular formula:C16H15N3O3S
Molecular Weight:329.37

112887-68-0 Synthesis

112887-68-0
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2-Thiophenecarboxylic acid, 5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-

138899-69-1
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Yield:138899-69-1 94%

Reaction Conditions:

with Tris buffer (tris(hydroxymethyl)aminomethane, ZnCl₂, aq. HCl, pH 7.3) at 30; for 2 h;carboxypeptidase G₂;

References:

Bisset, Graham M. F.;Pawelczak, Krzysztof;Jackman, Ann L.;Calvert, A. Hilary;Hughes, Leslie R. [Journal of Medicinal Chemistry,1992,vol. 35,# 5,p. 859 - 866]

2-Thiophenecarboxylic acid, 5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-, ethyl ester

167550-29-0
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138899-69-1
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References

6-Bromomethyl-3,4-dihydro-2-methyl-quinazolin-4-one

112888-43-4
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138899-69-1
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References

1235852-48-8 Synthesis

2-methyl-6-[(methylamino)methyl]-3,4-dihydroquinazolin-4-one

1235852-48-8
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138899-69-1
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References