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ChemicalBook CAS DataBase List 3-Isoxazolecarboxylic acid, 5-(hydroxymethyl)-, methyl ester (9CI)

3-Isoxazolecarboxylic acid, 5-(hydroxymethyl)-, methyl ester (9CI) synthesis

3synthesis methods
3-Isoxazolecarboxylic acid, 5-[[(tetrahydro-2H-pyran-2-yl)oxy]methyl]-, methyl ester

252769-66-7
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3-Isoxazolecarboxylic acid, 5-(hydroxymethyl)-, methyl ester (9CI)

139297-55-5
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Yield:139297-55-5 88%

Reaction Conditions:

with Amberlite H-15 in methanol at 50; for 5 h;Hydrolysis;

References:

Simoni, Daniele;Invidiata, Francesco Paolo;Rondanin, Riccardo;Grimaudo, Stefania;Cannizzo, Giuliana;Barbusca, Eleonora;Porretto, Ferdinando;D'Alessandro, Nicola;Tolomeo, Manlio [Journal of Medicinal Chemistry,1999,vol. 42,# 24,p. 4961 - 4969]