(E)-3-(4-chlorophenyl)-N-(3,4-dimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide synthesis

2synthesis methods

Product Name:(E)-3-(4-chlorophenyl)-N-(3,4-dimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide
CAS Number:1393587-68-2
Molecular formula:C19H18ClN4O3
Molecular Weight:385.8242

99-91-2 Synthesis

99-91-2
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$10.00/25g

(E)-3-(4-chlorophenyl)-N-(3,4-dimethoxybenzylidene)-1H-pyrazole-5-carbohydrazide

1393587-68-2
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Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: sodium methylate / tetrahydrofuran / 0.25 h / 0 °C / Inert atmosphere
1.2: 1 h / 0 - 20 °C / Inert atmosphere
2.1: hydrazine hydrate / ethanol / 6 h / Reflux
3.1: acetic acid / methanol / 6 h / Reflux

References:

Pathak, Ravindra B.;Chovatia;Parekh [Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,# 15,p. 5129 - 5133]

ETHYL 4-(4-CHLOROPHENYL)-2,4-DIOXOBUTANOATE

5814-38-0
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$64.00/250 mg

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References