ChemicalBook CAS DataBase List 2-Ethoxy-1-[[2'-[[[(ethoxycarbonyl)oxy]amino]iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid ethyl ester

2-Ethoxy-1-[[2'-[[[(ethoxycarbonyl)oxy]amino]iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid ethyl ester synthesis

3synthesis methods

Product Name:2-Ethoxy-1-[[2'-[[[(ethoxycarbonyl)oxy]amino]iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid ethyl ester
CAS Number:1403474-75-8
Molecular formula:C29H30N4O6
Molecular Weight:530.57

(Z)-Ethyl-2-ethoxy-3-((2'-(N'-hydroxycarbaMiMidoyl) biphenyl-4-yl) Methyl)-3H-benzo[d] iMidazole-4-carboxylate

1397836-41-7
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541-41-3
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$23.00/5g

2-Ethoxy-1-[[2'-[[[(ethoxycarbonyl)oxy]amino]iminomethyl][1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid ethyl ester

1403474-75-8
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Yield:1403474-75-8 82%

Reaction Conditions:

with triethylamine in dichloromethane at 20; for 2 h;

Steps:

8 Embodiment 8 Compound (4B, R = ethyl) preparation of

Compound (3B) 11.8 g, in the reaction bottle, by adding dichloromethane 100 ml, triethylamine 5.4 ml ethyl formate instillment chlorine 3.4 g, reaction at room temperature 2 hours. Adding water to 60 ml, stirring layered, methylene chloride level is separated, then the aqueous layer is extracted with methylene chloride, combined methylene chloride level, dry anhydrous sodium sulfate, filtered, concentrated to obtain crude, solid refined to obtain 11.2, yield 82.0%.

References:

CN103664792,2016,B Location in patent:Paragraph 0128-0130

1397836-41-7
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$514.00/1g

79-22-1
2 suppliers
$38.00/1000g

1403474-75-8
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References

139481-41-7 Synthesis

Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate

139481-41-7
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1403474-75-8
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References