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6-METHYL-5-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOLO[3,2-B][1,2,4]TRIAZOLE synthesis

3synthesis methods
1H-1,2,4-Triazole, 5-(2-propyn-1-ylthio)-

53918-08-4
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6-METHYL-5-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOLO[3,2-B][1,2,4]TRIAZOLE

1423121-05-4
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-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sulfuric acid / 0.83 h / 50 °C
2: copper acetylacetonate; potassium tert-butylate / N,N-dimethyl-formamide; 5,5-dimethyl-1,3-cyclohexadiene / 12.08 h / 20 - 120 °C / Inert atmosphere

References:

Xie, Zengyang;Zhu, Xiaojun;Guan, Yangfan;Zhu, Dunru;Hu, Hongwen;Lin, Chen;Pan, Yi;Jiang, Juli;Wang, Leyong [Organic and Biomolecular Chemistry,2013,vol. 11,# 8,p. 1390 - 1398]