4,6-Dichloro-2-(ethoxycarbonyl)-1H-indole-3-propanoic acid synthesis

3synthesis methods

Product Name:4,6-Dichloro-2-(ethoxycarbonyl)-1H-indole-3-propanoic acid
CAS Number:144989-41-3
Molecular formula:C14H13Cl2NO4
Molecular Weight:330.16

611-10-9
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$10.00/5g

4,6-Dichloro-2-(ethoxycarbonyl)-1H-indole-3-propanoic acid

144989-41-3
16 suppliers
$503.22/5MG

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: potassium hydroxide; water / ethanol / 0.5 h / 0 - 8 °C
2.1: sodium nitrite; hydrogenchloride / water / 0.33 h / 0 - 8 °C
2.2: 1 h / 0 - 40 °C
3.1: sulfuric acid / ethanol / 24 h / 100 °C

References:

Baqi, Younis;Alshaibani, Samer;Ritter, Kirsten;Abdelrahman, Aliaa;Spinrath, Andreas;Kostenis, Evi;Mueller, Christa E. [MedChemComm,2014,vol. 5,# 1,p. 86 - 92]

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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144989-41-3
16 suppliers
$503.22/5MG

References

611-10-9
406 suppliers
$10.00/5g

626-43-7
317 suppliers
$10.00/1g

144989-41-3
16 suppliers
$503.22/5MG

References