Benzeneacetonitrile, 3,4-dichloro-α-[3-[(tetrahydro-2H-pyran-2-yl)oxy]propyl]- synthesis
- Product Name:Benzeneacetonitrile, 3,4-dichloro-α-[3-[(tetrahydro-2H-pyran-2-yl)oxy]propyl]-
- CAS Number:146395-96-2
- Molecular formula:C16H19Cl2NO2
- Molecular Weight:328.23
110-87-2
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Yield:-
Steps:
Multi-step reaction with 2 steps
1: p-TsOH / tetrahydrofuran
2: 82 percent / NaH / tetrahydrofuran / 20 h / Ambient temperature
References:
Chen, Huai G.;Chung;Goel;Johnson;Kesten;Knobelsdorf;Lee;Rubin [Bioorganic and Medicinal Chemistry Letters,1997,vol. 7,# 5,p. 555 - 560]