5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID synthesis

2synthesis methods

Product Name:5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID
CAS Number:15070-84-5
Molecular formula:C10H8ClN3O2
Molecular Weight:237.64

2312-23-4 Synthesis

2312-23-4
216 suppliers
$7.00/10g

5-AMINO-1-(3-CHLORO-PHENYL)-1 H-PYRAZOLE-4-CARBOXYLIC ACID

15070-84-5
23 suppliers
$75.00/250 mg

Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium carbonate / ethanol / 20 h / Reflux
2: sodium hydroxide / ethanol; water / 24 h / Reflux

References:

Corte, James R.;Pinto, Donald J. P.;Fang, Tianan;Osuna, Honey;Yang, Wu;Wang, Yufeng;Lai, Amy;Clark, Charles G.;Sun, Jung-Hui;Rampulla, Richard;Mathur, Arvind;Kaspady, Mahammed;Neithnadka, Premsai Rai;Li, Yi-Xin Cindy;Rossi, Karen A.;Myers, Joseph E.;Sheriff, Steven;Lou, Zhen;Harper, Timothy W.;Huang, Christine;Zheng, Joanna J.;Bozarth, Jeffrey M.;Wu, Yiming;Wong, Pancras C.;Crain, Earl J.;Seiffert, Dietmar A.;Luettgen, Joseph M.;Lam, Patrick Y. S.;Wexler, Ruth R.;Ewing, William R. [Journal of Medicinal Chemistry,2020,vol. 63,# 2,p. 784 - 803]

ETHYL 5-AMINO-1-(3-CHLOROPHENYL)-1H-PYRAZOLE-4-CARBOXYLATE

15001-08-8
46 suppliers
$32.29/250mg

15070-84-5
23 suppliers
$75.00/250 mg

References