ChemicalBook CAS DataBase List Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-cyano-, methyl ester (9CI)

Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-cyano-, methyl ester (9CI) synthesis

7synthesis methods

Product Name:Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-cyano-, methyl ester (9CI)
CAS Number:156329-62-3
Molecular formula:C8H9NO2
Molecular Weight:151.16

DiMethyl bicyclo[1.1.1]pentane-1,3-dicarboxylate

115913-32-1
89 suppliers
$26.00/100mg

Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-cyano-, methyl ester (9CI)

156329-62-3
63 suppliers
$110.00/50mg

Yield:-

Steps:

Multi-step reaction with 4 steps
1: 86 percent / NaOH / tetrahydrofuran; methanol
2: C₂O₂Cl₂ / diethyl ether
3: NH₃ / CH₂Cl₂
4: 94 percent / SOCl₂

References:

Costantino, Gabriele;Maltoni, Katiuscia;Marinozzi, Maura;Camaioni, Emidio;Prezeau, Laurent;Pin, Jean-Philippe;Pellicciari, Roberto [Bioorganic and Medicinal Chemistry,2001,vol. 9,# 2,p. 221 - 227]

156329-77-0 Synthesis