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(4R,5R)-tert-butyl 4-(hydroxymethyl)-2,2,5-trimethyloxazolidine-3-carboxylate synthesis

1synthesis methods
(4S,5R)-3-tert-Butyl 4-methyl 2,2,5-trimethyloxazolidine-3,4-dicarboxylate

108149-61-7
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(4R,5R)-tert-butyl 4-(hydroxymethyl)-2,2,5-trimethyloxazolidine-3-carboxylate

157336-86-2
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Yield:157336-86-2 95%

Reaction Conditions:

with lithium aluminium hydride in tetrahydrofuran; for 0.333333 h;

References:

Kelly, Gilbert T.;Sharma, Vasudha;Watanabe, Coran M.H. [Bioorganic Chemistry,2008,vol. 36,# 1,p. 4 - 15]