2-Propenamide, 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)- synthesis

1synthesis methods

Product Name:2-Propenamide, 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-
CAS Number:157561-90-5
Molecular formula:C11H8N4O
Molecular Weight:212.21

1-(tert-Butoxycarbonyl)-3-formyl-7-azaindole, 3-Formyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester

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107-91-5 Synthesis

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2-Propenamide, 2-cyano-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-

157561-90-5
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Yield:157561-90-5 49%

Reaction Conditions:

with piperidine in tetrahydrofuran at 20; for 12 h;

References:

Miller, Rand M.;Paavilainen, Ville O.;Krishnan, Shyam;Serafimova, Iana M.;Taunton, Jack [Journal of the American Chemical Society,2013,vol. 135,# 14,p. 5298 - 5301] Location in patent:supporting information