(3S,6S,8aS)-6-(tert-butoxycarbonylamino)-5-oxooctahydroindolizine-3-carboxylic acid synthesis

2synthesis methods

Product Name:(3S,6S,8aS)-6-(tert-butoxycarbonylamino)-5-oxooctahydroindolizine-3-carboxylic acid
CAS Number:159303-50-1
Molecular formula:C14H22N2O5
Molecular Weight:298.33

METHYL (3S,6S,8AS)-6-[(TERT-BUTOXYCARBONYL)AMINO]-5-OXOOCTAHYDROINDOLIZINE-3-CARBOXYLATE

159303-54-5
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(3S,6S,8aS)-6-(tert-butoxycarbonylamino)-5-oxooctahydroindolizine-3-carboxylic acid

159303-50-1
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Yield:159303-50-1 92%

Reaction Conditions:

with lithium hydroxide in 1,4-dioxane at 0; for 1 h;

References:

Mir, Fatemeh M.;Atmuri, N. D. Prasad;Bourguet, Carine B.;Fores, Jennifer Rodon;Hou, Xin;Chemtob, Sylvain;Lubell, William D. [Journal of Medicinal Chemistry,2019,vol. 62,# 9,p. 4500 - 4525]

24424-99-5 Synthesis

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159303-50-1
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References