3,3-difluoro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one synthesis

1synthesis methods

Product Name:3,3-difluoro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one
CAS Number:1613639-41-0
Molecular formula:C14H16BF2NO3
Molecular Weight:295.09

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3,3-difluoro-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one

1613639-41-0
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Yield:1613639-41-0 68%

Reaction Conditions:

Stage #1: Ethyl bromodifluoroacetate;4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)anilinewith tris[2-phenylpyridinato-C²,N]iridium(III);sodium carbonate in dichloromethane at 20; for 24 h;Schlenk technique;Inert atmosphere;Irradiation;Sealed tube;
Stage #2: with ethanol at 60; for 6 h;

References:

Yu, Ling-Chao;Gu, Ji-Wei;Zhang, Shu;Zhang, Xingang [Journal of Organic Chemistry,2017,vol. 82,# 7,p. 3943 - 3949]