L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-,γ-lactone synthesis

1synthesis methods

Product Name:L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-,γ-lactone
CAS Number:166275-25-8
Molecular formula:C5H6F2O4
Molecular Weight:168.1

2-DEOXY-2,2-DIFLUORO-4,5-O-(1-METHYLETHYLIDENE)-L-THREO-PENTONIC ACID, ETHYL ESTER

166376-98-3
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L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-,γ-lactone

166275-25-8
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Yield:-

Reaction Conditions:

with Dowex-50 (H⁺) resin;water in methanol for 120 h;

References:

Kotra, Lakshmi P.;Xiang, Yuejun;Gary Newton;Schinazi, Raymond F.;Cheng, Yung-C.;Chu, Chung K. [Journal of Medicinal Chemistry,1997,vol. 40,# 22,p. 3635 - 3644]

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